AstraZeneca, Bavarian Nordic Partner in Cancer Pact
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AstraZeneca has partnered with Bavarian Nordic, a Kvistgaard, Denmark-based biopharmaceutical company, to investigate Bavarian’s targeted immunotherapy candidate, CV301, and durvalumab, AstraZeneca’s programmed death ligand-1 (PD-L1) inhibitor, in combination with maintenance…

Gilead’s Kite Pharma, Sangamo in Gene-Editing Pact Worth up to $3.16 Billion
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Kite Pharma, Gilead Sciences’ cell-therapy subsidiary, and Sangamo Therapeutics, a Richmond, California-based biotechnology company, have partnered to use Sangamo’s zinc finger nuclease (ZFN) technology platform for developing ex vivo cell…

AstraZeneca, Ionis in Pact for Antisense Drug for Kidney Disease
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AstraZeneca and Ionis Pharmaceuticals, a Carlsbad, California-based pharmaceutical company, have formed an agreement in which AstraZeneca will license Ionis’ IONIS-AZ5-2.5Rx, an antisense drug. IONIS-AZ5-2.5Rx was discovered by Ionis, and it…

Takeda, Wave Life Sciences in Oligonucleotide Drug Pact
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Takeda Pharmaceutical Company has formed a pact and multi-program option agreement with Wave Life Sciences, a Cambridge, Massachusetts-headquartered biopharmaceutical company, to develop antisense oligonucleotides for genetically defined neurological diseases. The…

AbbVie Forms Neurodegenerative Disease Pact Worth up to $1.1 Billion
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AbbVie and Voyager Therapeutics, a Cambridge, Massachusetts-headquartered clinical-stage gene-therapy company, have partnered to develop and commercialize vectorized antibodies directed against tau, a protein in the brain that promotes cellular stability,…

BMS, Nektar Therapeutics in Cancer Drug Pact Worth up to $3.63 Billion
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Bristol-Myers Squibb (BMS) and Nektar Therapeutics, a biopharmaceutical company, have partnered to develop and commercialize Nektar’s lead immuno-oncology drug candidate in combination with BMS’ immuno-oncology drugs, Opdivo (nivolumab) and Opdivo…

Roivant Partners for Diabetes Drug in up to $650-Million Deal
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Roivant Sciences, a Basel, Switzerland globally-headquartered biopharmaceutical company, and Poxel SA, a Lyon, France-based biopharmaceutical company developing treatments for metabolic disorders, have signed a development and license agreement for imeglimin,…

Takeda, Fujifilm in Pact for Regenerative Therapies
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Takeda Pharmaceutical and Fujifilm have partnered to develop regenerative medicine therapies using cardiomyocytes derived from induced pluripotent stem cells (iPSC) for treating heart failure. Takeda and Fujifilm signed a contract…

Rexahn Pharmaceuticals in Cancer Drug Development Pact
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Rexahn Pharmaceuticals, a Rockville, Maryland-headquartered clinical-stage biopharmaceutical company developing therapeutics for treating cancer, has formed a pact with Zhejiang Haichang Biotechnology, a Zhejiang, China-headquartered biopharmaceutical company, to develop Archexin (RX-0201)…

Seattle Genetics, Pieris in Immuno-Oncology Pact Worth up to $1.2 Billion
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Seattle Genetics, a Bothell, Washington-headquartered biopharmaceutical company, and Pieris Pharmaceuticals, a Boston, Massachusetts-headquartered clinical-stage biopharmaceutical company, have partnered to develop multiple targeted bispecific immuno-oncology treatments for solid tumors and blood…