AstraZeneca, PhaseBio Partner
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PhaseBio Pharmaceuticals, a clinical-stage biopharmaceutical company developing therapies for the treatment of orphan diseases, has signed an exclusive, worldwide license agreement with MedImmune, the global biologics research and development arm…

ImmunoVaccine, Leidos Expand Vaccine Pact
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Immunovaccine, a Nova Scotia, Canada-headquartered clinical-stage immunotherapy and vaccine company, is expanding its collaboration with Leidos, a science and technology company, to develop preventative, peptide-based malaria vaccine candidates. The United…

Biogen, Alkermes Partners for MS Drug
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Biogen and Alkermes have signed a license and collaboration agreement to develop and commercialize ALKS 8700, an oral, monomethyl fumarate small-drug molecule in Phase III development for treating relapsing forms…

Merck & Co. Partners for Autoimmune Diseases
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Merck & Co. and Cue Biopharma, a Cambridge, Massachusetts-headquartered immunotherapy company, have signed a research collaboration and license agreement in a deal worth up to $374 million. Under the deal,…

Bayer, Loxo in $1.55-Billion Oncology Pact
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Bayer has signed an agreement with Loxo Oncology, a Stamford, Connecticut-based biopharmaceutical company, to develop Loxo’s larotrectinib (LOXO-101) and LOXO-195 for treating patients with cancers harboring tropomyosin receptor kinase (TRK)…

Takeda in Pact for Needle-Free Drug Delivery
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Takeda Pharmaceutical Company and Portal Instruments, a Cambridge, Massachusetts-based medical equipment manufacturer, have agreed to develop and commercialize Portal’s needle-free drug delivery device for potential use with Takeda’s investigational or…

Pfizer Amends Gene-Therapy Pact
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Pfizer and Spark Therapeutics, a Philadelphia, Pennsylvania-headquartered biopharmaceutical company, have amended their license agreement for SPK-9001, an investigational gene therapy for hemophilia B. In December 2014, Pfizer signed an agreement…

Novartis Partners in Gene-Editing Pact
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Novartis and Homology Medicines, a Bedford, Massachusetts-based genetic medicines company focused on gene-editing and gene-therapy technology, have agreed to use Homology’s proprietary gene-editing technology to develop new treatments for select…

J&J, Zymeworks Partner for Bispecific Antibodies in $1-Billion-Plus Deal
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Janssen Biotech, one of the pharmaceutical companies of Johnson & Johnson, has signed a license agreement worth up to $1.4 billion with Zymeworks, a Vancouver, Canada-headquartered clinical-stage biopharmaceutical company. Under…

Sanofi, Principia Biopharma in MS, CNS Drug Pact Worth up to $805 Million
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Sanofi has partnered with Principia Biopharma, a South San Francisco, California-based clinical-stage biopharmaceutical company, to develop an experimental oral treatment for multiple sclerosis (MS) and other potential treatments for central…