The latest from CDMOs, CMOs, and suppliers featuring Solvias, Grand River Aseptic Manufacturing and Sharp.  

Biologics Manufacturing 
* Solvias To Build Biologics Testing Center 
* ExcellGene, Cytovance Partner for Cell-Line Development 
Formulation Development/Drug Product Manufacturing 
* GRAM To Build New Syringe & Cartridge Filling Center 
Packaging 
* Sharp To Expand Sterile Injectable Secondary Packaging Facility 

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Biologics Manufacturing 

Solvias To Build Biologics Testing Center 
Solvias, a Kaiseraugst, Switzerland-based provider of chemistry, manufacturing, and control (CMC) analytics, has announced that it is building a new biologics and cell & gene therapy testing center site in Research Triangle Park, North Carolina. 

The 50,000-square-foot facility, expected to be completed in 2025, will serve as Solvias’ North American hub for large-molecule analytical services. It will offer cell-based potency assays, sequencing capabilities, and related testing services supporting multiple biologic modalities.  

The new testing center will support characterization and release testing of cell- & gene-therapies and other advanced therapies, including adeno-associated virus gene therapies, mRNA therapies, and antibody drug conjugates. 

Source: Solvias 

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ExcellGene, Cytovance Partner for Cell-Line Development 
ExcellGene, a Monthey, Switzerland-based contract provider of mammalian cell-line development, has entered a strategic collaboration with Cytovance Biologics, an Oklahoma City, Oklahoma-based CDMO of biologics, to add ExcellGene’s transposon technologies to Cytovance’s capabilities.  

Under the agreement, Cytovance will gain access to ExcellGene’s Chinese hamster ovary (CHO) and human embryonic kidney (HEK) cell lines. The lines can be used to optimize protein quality, quantity, development timelines, and scalability for biomanufacturing through custom engineering to the specific requirements of a protein.  

Source: Cytovance Biologics 

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Formulation Development/Drug Product Manufacturing 

GRAM To Build New Syringe & Cartridge Filling Center 
Grand River Aseptic Manufacturing (GRAM), a CDMO of parenteral drug products, has announced that it will build a new syringe and cartridge filling center at the company’s site in Grand Rapids, Michigan. The center is 150,000 square feet and is designed to hold up to four syringe/cartridge filling and inspection lines. 

The new center is adjacent to GRAM’s existing 200,000-square-foot finishing and warehouse center. It brings the CDMO to five manufacturing facilities and more than 450,000 square feet of production space. GRAM estimates building construction will be complete in 2025, with new filling and inspection equipment installed in 2026. 

Source: Grand River Aseptic Manufacturing 

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Packaging 

Sharp To Expand Sterile Injectable Secondary Packaging Facility 
Sharp, a provider of contract packaging, clinical supply services, and small-scale sterile manufacturing, has announced an expansion plan for its site in Macungie, Pennsylvania, to increase its production capacity for sterile injectables secondary packaging.   

The expansion adds 157,500 square feet of open space to create a 315,000-square-foot facility, bringing Sharp’s total global footprint to more than 1.7 million square feet. The expansion will add capacity for secondary packaging activities, including vial labeling, prefilled syringe assembly & labeling, autoinjector/pen assembly & labeling, and injectables kitting and cartoning. 

Source: Sharp