Supplier News: WuXi STA, Delpharm, Asymchem & More
The latest from CDMOs, CMOs, and suppliers featuring WuXi STA, Delpharm. Asymchem, Abzena, Scorpion Biological Services, Formulated Solutions, and Polysciences.
Chemicals/Chemical API Manufacturing
* Asymchem Opens R&D Site
Biologics Manufacturing
* BMS Completes Mfg Facility Sale to Lotte Biologics
* Abzena Appoints New CEO
* Scorpion Biological Rebrands as Scorpius BioManufacturing
* Polysciences Launches Bioprocessing Brand Kyfora Bio
Formulation Development/Drug Product Manufacturing
* WuXi STA Opens Continuous Mfg Line for Oral Solids
* Delpharm Acquires Injectable Drug Mfg Facility
* Formulated Solutions To Acquire Drug-Product Mfg Facility
Chemicals/Chemical API Manufacturing
Asymchem Opens Early-Stage R&D Site
Asymchem Laboratories, a Tianjin, China-based CDMO of small-molecule active pharmaceutical ingredients (APIs), intermediates and drug products, has opened new site for early-stage R&D services, including chemical process development, pre-formulation study and formulation development for small molecules, peptides, and oligonucleotides in Woburn, Massachusetts. The site is part of Asymchem Boston, a wholly owned subsidiary of Asymchem Group.
After establishing the location in August 2022, the site is now ready for full operation. It has 6,000 square feet of existing lab space that includes process and analytical labs and space to expand an additional 4,500 square feet. Solid characterization and pre-formulation labs will be ready in the first quarter of 2023. By the third quarter of 2023, continued expansion will include a fully functional kilo lab, formulation R&D, and an oligonucleotide and peptide lab to support drug-substance and drug-product development and non-GMP production.
Source: Asymchem
Biologics Manufacturing
BMS Completes Mfg Facility Sale to Lotte Biologics
Bristol Myers Squibb (BMS) has completed the sale of its biomanufacturing facility in Syracuse, New York to Lotte Biologics, a Lotte Corporation company, and new established CDMO. Lotte Corporation is a Seoul, Korea-based holding company of Lotte Group with holdings in chemicals, food & beverage, retail, and hotel & services.
As part of the transaction, Lotte has offered all employees at the site employment within its business. Lotte acquired the Syracuse site’s operations and assets, which includes the property, plant and equipment. BMS formed a newly established CMO relationship with Lotte, under which Lotte will manufacture product for BMS at the Syracuse facility.
Source: Bristol Myers Squibb
Abzena Appoints New CEO
Abzena, a San Diego, California-based CDMO of biologics and antibody drug conjugates, has appointed Matthew Stober, formerly CEO of CastleVax, a New York City-based vaccine company, and Istari Oncology, a Morrisville, North Carolina-based bio/pharmaceutical company, as its new CEO.
Earlier in his career, Stober held executive positions at Merck & Co., GlaxoSmithKline, Novartis, and helped lead the operational turnaround of Hospira, resulting in the eventual sale of Hospira to Pfizer for $17 billion.
Source: Abzena
Scorpion Biological Rebrands as Scorpius BioManufacturing
Scorpion Biological Services, a San Antonio, Texas-based CDMO of biologics, has changed its name to Scorpius BioManufacturing, reflecting the company’s recently expanded manufacturing capabilities and the opening of its new biomanufacturing facility in San Antonio in October (October 2022).
The new facility offers GCP, GLP and GMP biomanufacturing capabilities in both mammalian and microbial modalities. Suites and equipment trains are flexible, with bioreactor sizes ranging from 50 L up to 2,000 L, Scorpius provides services to manufacture a wide range of products, including cell therapies, recombinant proteins from mammalian or microbial systems, and DNA vectors.
Source: Scorpius BioManufacturing
Polysciences Launches Bioprocessing Brand Kyfora Bio
Polysciences, a Pennsylvania-based manufacturer of specialty chemicals for research, in vitro diagnostics, and medical device applications, has launched a new brand, Kyfora Bio, representing its product offerings to the bioprocessing market.
Kyfora Bio will be based in Horsham, Pennsylvania, and will focus on the synthesis of cationic polymers, lipids, and other materials used in nucleic acid delivery for cell and gene therapies. It will occupy a 45,000-square-foot cGMP facility outfitted with administrative offices, R&D laboratories, manufacturing suites, and quality control laboratories for chemical and biological performance testing.
Source: Kyfora Bio
Formulation Development/Drug Product Manufacturing
WuXi STA Opens Continuous Mfg Line for Oral Solids
WuXi STA, a Wuxi, China-based CDMO of active pharmaceutical ingredients (APIs) and drug products and a subsidiary of WuXi AppTec, has begun operation of its first drug-product continuous manufacturing line for oral solids at its drug product site in Wuxi City, China.
WuXi STA’s continuous manufacturing line features continuous direct compression equipment with unit operations, including dispensing, blending, lubrication, tablet compression, and coating.
Source: WuXi STA
Delpharm Acquires Injectable Drug Mfg Facility
Delpharm, a Boulogne-Billancourt, France-based CDMO of drug products, has acquired an injectable drug-development facility in Leiden, the Netherlands from Dr Reddy’s Laboratories. This facility employs 40 personnel and is in a 3,500-square-meter unit, equipped with technologies to develop injectable formulations for small and large molecules and to manufacture small batches for clinical trials.
With the acquisition of the Leiden site, Delpharm is now positioned as a complete player in injectables, from formulation, analytical development, Phase I clinical batches manufacturing, to production in one of the company’s four injectable plants (three in France and one in Canada).
Source: Delpharm
Formulated Solutions To Acquire Drug-Product Mfg Facility
Formulated Solutions, a Largo, Florida-based CDMO of drug products for consumer healthcare products, has agreed to acquire a 455,000-square-foot production facility in Cleveland, Tennessee, for liquids, semisolids, aerosols, bag-on-valve products, and metered-dose nasal sprays production facility.
The facility has capabilities for blending of liquids, semisolids, and suspensions and packaging capabilities for flexible tubes, liquid-fill bottles, and metered-dose sprays to traditional aerosol and bag-on-valve aerosol delivery systems that can support a large variety of development and commercial supply programs.
Source: Formulated Solutions
