Vetter has released Vetter-Ject, a closure system for prefilled syringes. The closure system uses a baked-in siliconization process for the glass barrel, thereby requiring less silicon oil than commonly used, which makes the system suitable for silicon-sensitive drug products. The silicon content of the syringe can also be adjusted. The amount of silicon used; as well as the related particle load, can be reduced by up to 80% when compared to the standard siliconization process applied to conventional syringe systems, according to Vetter.

Consisting of a needle hub and a needle shield, the new syringe closure system is partly produced by means of a 2-component injection molding process of polypropylene and thermoplastic elastomer. It consists of a tamper-evident closure system, combined with an integrated staked needle. Vetter-Ject can be used with a wide range of primary packaging options, such as different stoppers and glass barrels, which can be customized according to the needs of the drug product.

Source: Vetter