Merck KGaA, Forty Seven Inc. in Ovarian Cancer Pact
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Merck KGaA and Forty Seven Inc., a Menlo Park, California-headquartered clinical-stage company developing immuno-oncology treatments, have agreed to conduct a clinical trial combining Hu5F9-G4, a monoclonal antibody against the CD47…

BeiGene, Mirati in Immuno-Oncology Pact
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BeiGene, a Beijing, China-headquartered clinical-stage biopharmaceutical company focused on immuno-oncology, and Mirati Therapeutics, a San Diego, California-headquartered clinical-stage oncology company, have signed an agreement for the development, manufacturing, and commercialization…

PharmaIN, Shionogi & Co. Partner
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PharmaIN Corporation, a Bothell, Washington-headquartered development-stage biopharmaceutical company, and Shionogi & Co., a pharmaceutical company, have signed an agreement with an exclusive two-year option to negotiate a license for a…

Sanofi, Alnylam Restructure RNAi Therapeutics Pact for Rare Diseases
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Sanofi and Alnylam Pharmaceuticals, a Cambridge, Massachusetts-based biopharmaceutical company focused on RNAi therapeutics, have announced a restructuring of their RNAi therapeutics alliance to streamline development and commercialization of certain products…

Amgen, Biocartis Sign Companion Diagnostic Pact
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Amgen has signed a companion diagnostic (CDx) development agreement with Biocartis Group, a Mechelen, Belgium-headquartered molecular diagnostics company, for Biocartis’ Idylla RAS biomarker tests. The aim of the agreement is…

Tesaro, Teneobio in Immuno-Oncology Pact
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Tesaro, a San Antonio, Texas-headquartered oncology-focused biopharmaceutical company, has signed a research and license agreement with Teneobio, a Menlo Park, California-headquartered biotechnology company developing multi-specific antibody therapeutics. The companies have…

United Therapeutics, Corsair Pharma in Prodrugs Pact
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United Therapeutics Corporation, a Silver Spring, Maryland-headquartered biotechnology company developing therapies for treating pulmonary arterial hypertension (PAH), and Corsair Pharma, a biopharmaceutical company developing a transdermal treprostinil prodrug, have signed…

Pfizer, Sangamo in Gene-Therapy Pact
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Pfizer and Sangamo Therapeutics, a Richmond, California-based biotechnology company, have partnered to develop a potential gene therapy using zinc-finger-protein transcription factors (ZFP-TFs) to treat amyotrophic lateral sclerosis (ALS) and frontotemporal…

Array BioPharma, Aslan Pharmaceuticals Expand Immuno-Oncology Pact
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Array BioPharma, a Boulder, Colorado-based biopharmaceutical company developing small-molecule anti-cancer therapies, has granted Aslan Pharmaceuticals, a Singapore-based biotechnology company focused on immunotherapies and targeted agents for Asia-prevalent tumor types, full…

Takeda, Denali Therapeutics Partner for Neurodegenerative Diseases
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Takeda Pharmaceutical has signed an agreement with Denali Therapeutics, a San Francisco, California-headquartered biotechnology company developing drugs for treating neurodegenerative diseases, to develop and commercialize up to three specified therapeutic…